List of matches in this round
- TimeMatch
- 5. Juni 2022
- 15:00Frankfurt Galaxy26:29Rhein Fire
- 12. Juni 2022
- 15:00Leipzig Kings17:28Rhein Fire
- 19. Juni 2022
- 15:00Rhein Fire42:18Istanbul Rams
- 26. Juni 2022
- 15:00Rhein Fire13:17Barcelona Dragons
- 3. Juli 2022
- 15:00Hamburg Seadevils42:15Rhein Fire
- 24. Juli 2022
- 15:00Rhein Fire16:40Hamburg Seadevils
- 30. Juli 2022
- 15:00Barcelona Dragons33:23Rhein Fire
- 13. August 2022
- 15:00Istanbul Rams32:50Rhein Fire
- 21. August 2022
- 15:00Rhein Fire23:21Frankfurt Galaxy
- 27. August 2022
- 15:00Cologne Centurions37:59Rhein Fire
- 4. September 2022
- 15:00Rhein Fire31:34Leipzig Kings